Our data suggest that the cannabinoid system is implicated in the psychoactive properties of caffeine and in the ability of caffeine to reduce the pathological consequences of stress.
Chronic caffeine assumption sensitized GABAergic synapses to the presynaptic effect of cannabinoid CB1 receptor stimulation by exo- and endocannabinoids.
The synaptic effects of caffeine were slowly reversible after its removal from the drinking solution.
Furthermore, although exposure to caffeine for only 24h did not produce measurable changes of the sensitivity of cannabinoid CB1 receptors, it was able to contrast the down-regulation of CB1 receptor-mediated responses after social defeat stress.
I copied the rest from bloommedicinals.com, just the relevant bits. Also added the links to the studies and the pages with additional descriptions.
TL;DR:
Low levels of caffeine can help to maximize the effects of THC, but too much caffeine can lessen the impact of your cannabis
Caffeine and THC can both increase dopamine levels, but too much at once can trigger anxiety, agitation, and paranoia
What Happens When You Smoke Weed and Drink Coffee?
Since coffee and cannabis may offer so many health benefits on their own, you might think it’s safe to assume that enjoying a little bit of weed with your coffee would be okay. The reality is … it might be safe for most, but not for all. Here’s why.
THC and coffee can boost the amount of dopamine in our systems. Although dopamine can promote feelings of happiness and euphoria, too much of it at once can trigger anxiety, agitation, and paranoia. In addition, both caffeine and THC can both increase your blood pressure and heart rate.
This is why many doctors advise that those with heart conditions and those at risk of heart arrhythmia or stroke, should not mix caffeine and THC. So, if you’re new to mixing coffee and cannabis, it’s important to consult your doctor to make sure it makes sense for you. If it does, begin with lower amounts of coffee and cannabis than you would normally consume on their own. Then if needed, you can increase your dosage slowly.
Back in 2014, a study was conducted to measure the effects of mixing caffeine and cannabis on squirrel monkeys. The results of this study were published in the Journal of Neuroscience. (also described here)
The monkeys were given the ability to self administer cannabis whenever they wanted. All they had to do was to pull on a lever. When the monkeys were given low doses of a substance similar to caffeine, they seemed less likely to reach for the THC. But, when they received high doses of caffeine, they seemed to reach for that lever more often.
Then in 2018, a study led by Marilyn Cornelis at Northwestern University’s Feinberg School of Medicine seemed to back up these findings. This time, the study examined the effects of mixing cannabis and coffee on humans. It found that the more caffeine people consumed, the less cannabis their body was able to metabolize. (also described here)
So, although small amounts of caffeine can help your THC go a long way – too much caffeine can lessen its effects.
Used weed for the past 20ish years to make my damned brain shut up and for sleep issues. I quit about 4 months ago after the realization that I might have adhd. Wanted to see if things got better after stopping. They really didn’t. I had no clue that this could be the source of my issues until recently so now I’m over here waiting for an appointment. Self medication and drug/alcohol use is apparently really common with undiagnosed adhd. But damned do I miss it. The first couple weeks where rough, and i do feel like I was having some withdrawal effects from quitting despite people saying it’s not addictive. It was literally giving me easy dopamine so your comment makes alot of sense.
This is where I’m at rn but I’m worried about trying to get medication to treat it.
Since I was a kid I’ve always had issues with motivation and organization. My default state is moderate messiness and disorganization, weed just makes me not feel as bad about it and stop stressing myself out.
I hear you on the meds. I’m not sure I’m to enthused about those but people keep saying they help so I don’t know. I also know I need to change my behavioral habits I’ve developed over the years but it’s not easy. Just going to go with whatever the psychiatrist says and gk from there. I’m just so tired of my own crap at this point. And yeah, weed made it easier to just be. And I don’t think you have to take medication if you don’t want too. Don’t think they will force it on you.
Hate that this has to be a worry. Makes it harder for people that actually need help to get help. If I was drug seeking there are easier options than going for a freaking adhd assessment. Oh well, try not to stress over it, and I know it’s hard not too but you can always go to another Dr. Just makes it a pain in the ass. Good luck of you do decide to go through with it.
Prolonged use of use of weed can reduce you brains motivation system which is something that people with ADHD already have a problem with. Long term use of weed may be risky idea for someone with ADHD.
source: my doctor who gave me my medical card and my psychiatrist
Though I did read a thing that did say people with adhd do have a higher occurrence of marijuana use, despite its negative effects on their symptoms (with potential permanent impacts for users under 25)
Weed is not going to ruin your life the same way like benzos and alcohol would. If you smoke everyday then you probably aren’t very productive, but you are not actively ruining your life.
Weed is dangerous because of how safe it is. It makes you ok with being bored and not progressing/growing as a person. Alcohol addiction will straight up make you homeless.
Ive honestly stopped buying the different strains have different effects talk. No matter what I smoke I get stoned and lazy af. Not that that’s bad, it’s just what happens.
Good that you know your self in that case. Not all bodies react the same way. I know folks who can’t get high from smoking but do from edibles, and vice versa.
I’ve definitely noticed a slight difference but no strain is going to suddenly make you productive. Maybe you want to be productive but you feel tired and crappy because you’re too sober, and getting a fix helps. Doesn’t mean the weed is actually helping you it just means you’re addicted
Weed is illegal federally, but it keeps getting produced at a state level. This really worries me, si to try to rectify this situation, I have just been buying and burning as much as I can. I don’t know how much of an effect its having because I just keep seeing more pop up.
I will continue despite it seeming more and more like a fools errand.
Why is it your problem? I’m not trying to be judgemental, I just don’t see why I should care what others do? It’s not like every stoner is blowing the smoke in your face.
not really a woosh, I didn’t think that part out fully. I was talking from my perspective where I would be respectful, just as I am with vaping. I know in some parts, i’ve heard it can be really bad. Screw people who just blow it everywhere and make places stink. However there are nearly oderless ways of smoking (particularly vaping) where a smoker can be respectful about it, and just keep it in there car (leave it in your driveway, never drive high). In this case, I don’t see why someone should be upset at the respectfull stoners.
There’s withdrawal but of the four drugs i have been physically addicted to (caffeine, weed, nicotine, and SSRIs) it’s the only one I can cold turkey in under a week and feel fine.
yes, I used to have the same experience. regular smoking and then stopping for a bit was fine. but it didn’t leave my mind. It’s not physically addictive, but neither is shopping or video games, or gambling, yet so many people are addicts
I don’t drink coffee or tea, but I usually drink caffeinated soda with food. I visited another country a few years back where soda isn’t usually drank except in special occasions like at parties. I couldn’t figure out why I had such a bad headache for the first few days. I thought the caffeine content from soda would be low enough that I wouldn’t have withdrawals. Finally on about day 5 I decided to have tea with my breakfast, and no headache that day. That was when I realized what a caffeine withdrawal headache felt like, and I finally realized why I get headaches if I don’t have lunch at my regular time (when I usually have my soda).
I really wish I could get caffeine free cola, because I don’t even want the caffeine. I just want the cola flavor. But it seems the only caffeine free cola that is sold in stores is also diet, which I don’t like the taste of. They sell caffeine free, non-diet cola online, but at absurd prices.
I’m in the US. It isn’t available in any stores here. You can get it online for $20 for a 12 pack. Regular price for coke right now is $7 for a 12 pack, which is already shockingly high. About 10-15 years ago you could get 48 cans for $11.
Depends on how bad your caffeine addiction is. I tried cold turkey when I had a tooth pulled when I was drinking a pot of coffee a day.
A week in bed on Vicodin and Percocet, didn’t touch that headache and it didn’t improve or go away until I drank coffee.
Oddly, I ate a large bag of mushrooms and got tazed by the cops one night. Ended up in the psych ward. Was able to cold turkey the coffee after that. Not sure if it was the mushrooms or the juice from the tazer.
Yeah, I’m not sure if Vicodin or perc would help a migraine, different pain killers help in different ways. I think opiods are the least helpful when it comes to migraines, if I remember correctly.
Caffeine isn’t addictive. Your body acclimates to long term usage, and you will experience some withdrawal symptoms but this is classified as a dependency and not an addiction as it does not trigger the reward mechanisms like weed and or methamphetamine does. It’s an important distinction and is why coffee and tea are often served at [Addiction] Anonymous meetings.
It’s both. Nicotine is also both. Note how people at AA still often smoke. And how much coffee they’ll pound even after dinner.
The only drug I misclassified is SSRIs. Which don’t trigger the dopamine reward system.
And my comment was in light of OP and common language usage. People say heroin addiction and they mean heroin dependency. It doesn’t help anyone to be pedantic about these two words. And I say that as someone who has taken college level classes on pharmacology and alcohol and drug dependence and is very aware of the technical differences used professionally.
Well it really isn’t addictive as opiates for example are. You wont become chemically dependant to it. The kind of addiction it causes is the same one that social media, TV, gaming, etc might cause. It becomes an habit and you get used to that. I know this is a simplification but this is how I see it.
Why? My guy, have you seen the world? Have you seen how people treat each other? If you don’t smoke I don’t know what the fuck you’re doing, but if it’s to be “a moral and upstanding citizen” I both laugh and cry at your blissful ignorance.
Of course i have nothing against people who take weed, i just personally don’t like the feeling of alcohol/weed or anything like that. Makes me feel like I’m not in control of myself. I hate not being in control of myself.
I don’t care if anyone smokes. Just don’t annoy me with it. People smoking in public places and giving you free lung cancer is my worst pet peeve.
Thats why I hate smoking more than drinking. Drinking doesn’t make me want to cough my lungs out and doesn’t endanger me directly when someone does it. Smoking does.
I seriously doubt you’re near enough second hand pot smoke to get cancer compared to like whatever’s ins the water or like idk I feel like micro plastics in your blood should be a bigger concern. But hey everyone’s entitled to their own version of paranoia. Gotta keep these meat suits living as long as possible, right?
You see, I think drugs have done some good things for us. I really do. And if you don’t believe drugs have done good things for us, do me a favor. Go home tonight. Take all your albums, all your tapes and all your CDs and burn them. 'Cause you know what, the musicians that made all that great music that’s enhanced your lives throughout the years? Rrrrrrrrrrrreal fucking high on drugs. The Beatles were so fucking high they let Ringo sing a few tunes.
-Bill Hicks
I’m a medical user and I’m absolutely admitting to my dependance on it. Because otherwise I’d be in pain and not in complete control of my body and mind. I never get red eyes, tho
Personally I thought weed was very addictive, but not in the traditional sense.
Take coffee for instance. When I stopped drinking coffee I had headaches, was a dick for a few days, but that’s it. Which is pretty easy compared to, say, heroin (so I hear).
With weed, I didn’t have any of that, but I craved the relaxation it brought. The feeling of not giving a fuck about anything for a few hours was great, and I longed for it. I still long for it sometimes. And I think that’s the dangerous thing about weed being labeled as “non-addictive.”
Just because you don’t have a physical reaction to abstaining, doesn’t mean the emotional reliance is nothing.
I feel exactly the same way. Much less of a physical addiction for me. For a long time I was in the “not addictive” camp, but realized that there was a reason that I was resistant to stopping. I’ll still partake, but I’m more mindful about recognizing when its becoming a dependance issue again.
That’s pretty much a habit, I also get uncomfortable when I have to go out when I always have that day free. Peanut butter cups might not be a good example because the sugar is really bad for humans.
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It’s a choice. I could stop any time I like!
Yeah, I just voluntarily chose to do it for 9 years every single day, even though I didn’t actually like it anymore the last 2 of those.
I drink coffee everyday. I will rise my cup of Joe to the stoner. I get you bro.
Cheers! I’d like to pass on this info though, for anyone who enjoys both like myself:
Caffeine drinking potentiates cannabinoid transmission: interaction with stress effects - Neuropharmacology 2009
I copied the rest from bloommedicinals.com, just the relevant bits. Also added the links to the studies and the pages with additional descriptions.
TL;DR:
Thing is, caffeine is physically addictive. Weed is not.
But you can make a habit out of anything.
Weed has psychological withdrawal effects https://lemm.ee/comment/913303
So does breaking a nail chewing habit. Brains are funky things.
It’s an easy answer really. I’m removed
Because a lot of them probably have undiagnosed ADHD or Autism and don’t realize what they’re trying to help by doing it or why it’s helping.
Used weed for the past 20ish years to make my damned brain shut up and for sleep issues. I quit about 4 months ago after the realization that I might have adhd. Wanted to see if things got better after stopping. They really didn’t. I had no clue that this could be the source of my issues until recently so now I’m over here waiting for an appointment. Self medication and drug/alcohol use is apparently really common with undiagnosed adhd. But damned do I miss it. The first couple weeks where rough, and i do feel like I was having some withdrawal effects from quitting despite people saying it’s not addictive. It was literally giving me easy dopamine so your comment makes alot of sense.
This is where I’m at rn but I’m worried about trying to get medication to treat it.
Since I was a kid I’ve always had issues with motivation and organization. My default state is moderate messiness and disorganization, weed just makes me not feel as bad about it and stop stressing myself out.
I hear you on the meds. I’m not sure I’m to enthused about those but people keep saying they help so I don’t know. I also know I need to change my behavioral habits I’ve developed over the years but it’s not easy. Just going to go with whatever the psychiatrist says and gk from there. I’m just so tired of my own crap at this point. And yeah, weed made it easier to just be. And I don’t think you have to take medication if you don’t want too. Don’t think they will force it on you.
It’s less worried about being forced and more worried about them thinking I’m drug seeking, it’s happened to friends of mine who have asked about it.
Hate that this has to be a worry. Makes it harder for people that actually need help to get help. If I was drug seeking there are easier options than going for a freaking adhd assessment. Oh well, try not to stress over it, and I know it’s hard not too but you can always go to another Dr. Just makes it a pain in the ass. Good luck of you do decide to go through with it.
As a guy with ADHD and had a medical license… yup. Pretty much.
Prolonged use of use of weed can reduce you brains motivation system which is something that people with ADHD already have a problem with. Long term use of weed may be risky idea for someone with ADHD. source: my doctor who gave me my medical card and my psychiatrist
Though I did read a thing that did say people with adhd do have a higher occurrence of marijuana use, despite its negative effects on their symptoms (with potential permanent impacts for users under 25)
Permanently or temporarily after you quit?
I think it fixes itself when quitting for a long enough time but I’m not entirely sure. I’d ask a doctor.
Because it helps me focus during tasks and let’s me vibe when I need to relax.
Sounds like how lots of people use nicotine
If you ignore my glaring lack of lung cancer and ability to take breaks without suffering withdrawal symptoms, then sure.
Weed is not going to ruin your life the same way like benzos and alcohol would. If you smoke everyday then you probably aren’t very productive, but you are not actively ruining your life.
Weed is dangerous because of how safe it is. It makes you ok with being bored and not progressing/growing as a person. Alcohol addiction will straight up make you homeless.
If you aren’t very productive you haven’t found the right strain… or you’re eating edibles.
Ive honestly stopped buying the different strains have different effects talk. No matter what I smoke I get stoned and lazy af. Not that that’s bad, it’s just what happens.
Good that you know your self in that case. Not all bodies react the same way. I know folks who can’t get high from smoking but do from edibles, and vice versa.
Still get stoned from edibles unless I throw some other stuff in the mix.
Same here. Tried indica because it “slows you down” vs sativa, and all the hybrids in between. All are the same affects
I’ve definitely noticed a slight difference but no strain is going to suddenly make you productive. Maybe you want to be productive but you feel tired and crappy because you’re too sober, and getting a fix helps. Doesn’t mean the weed is actually helping you it just means you’re addicted
Someone else said it, but I agree:
if alcohol were discovered today, it would 100% be illegal in no time
Weed is illegal federally, but it keeps getting produced at a state level. This really worries me, si to try to rectify this situation, I have just been buying and burning as much as I can. I don’t know how much of an effect its having because I just keep seeing more pop up.
I will continue despite it seeming more and more like a fools errand.
Notice that this previous comment holds with certainty for the United States Of America. Your mileage may vary depending on your area.
If for instance on the other hand, you live in The Netherlands, having small amounts of cannabis to use is legal.
So glad that isn’t the case here. Burning small amounts would get me no where.
Why is it your problem? I’m not trying to be judgemental, I just don’t see why I should care what others do? It’s not like every stoner is blowing the smoke in your face.
Why is it who’s problem? Sorry I am a little confused. This damn smoke keeps getting in my eyes. Maybe I should burn this outdoors instead.
Woosh
not really a woosh, I didn’t think that part out fully. I was talking from my perspective where I would be respectful, just as I am with vaping. I know in some parts, i’ve heard it can be really bad. Screw people who just blow it everywhere and make places stink. However there are nearly oderless ways of smoking (particularly vaping) where a smoker can be respectful about it, and just keep it in there car (leave it in your driveway, never drive high). In this case, I don’t see why someone should be upset at the respectfull stoners.
I’m with you brother. You don’t need to walk this brave path alone.
There’s withdrawal but of the four drugs i have been physically addicted to (caffeine, weed, nicotine, and SSRIs) it’s the only one I can cold turkey in under a week and feel fine.
yes, I used to have the same experience. regular smoking and then stopping for a bit was fine. but it didn’t leave my mind. It’s not physically addictive, but neither is shopping or video games, or gambling, yet so many people are addicts
Weed is physically addictive. Withdrawal is very mild and only lasts a few days but it can happen with heavy use.
I didn’t experience it until I got into edibles and vaping concentrates and I had used weed regularly off and on for twenty years at that point.
So it takes heavy use, but physical withdrawal is a real thing with weed. But as I said, it’s the only drug I’ve been addicted to I would cold turkey.
Yeah, caffeine cold turkey is unexpectedly tough.
I don’t drink coffee or tea, but I usually drink caffeinated soda with food. I visited another country a few years back where soda isn’t usually drank except in special occasions like at parties. I couldn’t figure out why I had such a bad headache for the first few days. I thought the caffeine content from soda would be low enough that I wouldn’t have withdrawals. Finally on about day 5 I decided to have tea with my breakfast, and no headache that day. That was when I realized what a caffeine withdrawal headache felt like, and I finally realized why I get headaches if I don’t have lunch at my regular time (when I usually have my soda).
I really wish I could get caffeine free cola, because I don’t even want the caffeine. I just want the cola flavor. But it seems the only caffeine free cola that is sold in stores is also diet, which I don’t like the taste of. They sell caffeine free, non-diet cola online, but at absurd prices.
Not trying to be a dick, but “I don’t like the taste of diet soda” feels like a very minor inconvenience for fighting an addiction you want to shake
Aspartame likely causes cancer, probably worse for you than actual sugar. But the dosage of each makes all the difference.
I don’t care enough to shake the addiction to caffeine. It would be nice to, but not something I care enough to put much effort into.
£5 for an 8 pack of coke zero decaf at the supermarket, I just checked. What and where are you looking at?
I’m in the US. It isn’t available in any stores here. You can get it online for $20 for a 12 pack. Regular price for coke right now is $7 for a 12 pack, which is already shockingly high. About 10-15 years ago you could get 48 cans for $11.
It’s not so bad if you pop a Tylenol the first couple of days, just to get you through the caffeine migraine phase.
Depends on how bad your caffeine addiction is. I tried cold turkey when I had a tooth pulled when I was drinking a pot of coffee a day.
A week in bed on Vicodin and Percocet, didn’t touch that headache and it didn’t improve or go away until I drank coffee.
Oddly, I ate a large bag of mushrooms and got tazed by the cops one night. Ended up in the psych ward. Was able to cold turkey the coffee after that. Not sure if it was the mushrooms or the juice from the tazer.
Yeah, I’m not sure if Vicodin or perc would help a migraine, different pain killers help in different ways. I think opiods are the least helpful when it comes to migraines, if I remember correctly.
Vicodin has Tylenol in it
I confirm. Taking opioids against migraine gives you still a migraine, but on opioids. Not recommended.
Vicodin has Tylenol in it
but we’re not talking about migraines.
we’re talking about caffeine withdrawal headaches.
neither of which are 💯 understood but that doesn’t make them the same.
plus, Vicodin has Tylenol in it. so i was taking Tylenol.
Caffeine withdrawal can absolutely trigger migraines, easily.
Not sure about the Tylenol in Vic, but just that opioids in general don’t work well. You can easily Google it.
Caffeine isn’t addictive. Your body acclimates to long term usage, and you will experience some withdrawal symptoms but this is classified as a dependency and not an addiction as it does not trigger the reward mechanisms like weed and or methamphetamine does. It’s an important distinction and is why coffee and tea are often served at [Addiction] Anonymous meetings.
It’s both. Nicotine is also both. Note how people at AA still often smoke. And how much coffee they’ll pound even after dinner.
The only drug I misclassified is SSRIs. Which don’t trigger the dopamine reward system.
And my comment was in light of OP and common language usage. People say heroin addiction and they mean heroin dependency. It doesn’t help anyone to be pedantic about these two words. And I say that as someone who has taken college level classes on pharmacology and alcohol and drug dependence and is very aware of the technical differences used professionally.
true it’s probably the easiest drug to quit but there is a strong psychological addiction
Well it really isn’t addictive as opiates for example are. You wont become chemically dependant to it. The kind of addiction it causes is the same one that social media, TV, gaming, etc might cause. It becomes an habit and you get used to that. I know this is a simplification but this is how I see it.
I think part of it for a lot of them is they smoke it with tobacco too so it’s just as addictive as regular smoking anyway
Why? My guy, have you seen the world? Have you seen how people treat each other? If you don’t smoke I don’t know what the fuck you’re doing, but if it’s to be “a moral and upstanding citizen” I both laugh and cry at your blissful ignorance.
I don’t like smoking.
me neither
Don’t like how it feels.
Fair enough to all three of you, just let me have my weed in peace.
Of course i have nothing against people who take weed, i just personally don’t like the feeling of alcohol/weed or anything like that. Makes me feel like I’m not in control of myself. I hate not being in control of myself.
You need to take some shrooms and realize you’re never really in control of yourself
Absolutely not
I don’t care if anyone smokes. Just don’t annoy me with it. People smoking in public places and giving you free lung cancer is my worst pet peeve.
Thats why I hate smoking more than drinking. Drinking doesn’t make me want to cough my lungs out and doesn’t endanger me directly when someone does it. Smoking does.
I seriously doubt you’re near enough second hand pot smoke to get cancer compared to like whatever’s ins the water or like idk I feel like micro plastics in your blood should be a bigger concern. But hey everyone’s entitled to their own version of paranoia. Gotta keep these meat suits living as long as possible, right?
You see, I think drugs have done some good things for us. I really do. And if you don’t believe drugs have done good things for us, do me a favor. Go home tonight. Take all your albums, all your tapes and all your CDs and burn them. 'Cause you know what, the musicians that made all that great music that’s enhanced your lives throughout the years? Rrrrrrrrrrrreal fucking high on drugs. The Beatles were so fucking high they let Ringo sing a few tunes. -Bill Hicks
A Bill Hicks quote is always appreciated.
I’m a medical user and I’m absolutely admitting to my dependance on it. Because otherwise I’d be in pain and not in complete control of my body and mind. I never get red eyes, tho
I thought this shit was left at reddit
Because habitual doesn’t mean addictive, I also have a problem with peanut butter cups.
Personally I thought weed was very addictive, but not in the traditional sense.
Take coffee for instance. When I stopped drinking coffee I had headaches, was a dick for a few days, but that’s it. Which is pretty easy compared to, say, heroin (so I hear).
With weed, I didn’t have any of that, but I craved the relaxation it brought. The feeling of not giving a fuck about anything for a few hours was great, and I longed for it. I still long for it sometimes. And I think that’s the dangerous thing about weed being labeled as “non-addictive.”
Just because you don’t have a physical reaction to abstaining, doesn’t mean the emotional reliance is nothing.
You can get psychologically “addicted” to anything.
Im not sure “addicted” is the right word.
Yeah, perhaps you’re right.
It’s hard to break habits. I’m not naive though, I know what it feels like, it’s a mind battle.
I feel exactly the same way. Much less of a physical addiction for me. For a long time I was in the “not addictive” camp, but realized that there was a reason that I was resistant to stopping. I’ll still partake, but I’m more mindful about recognizing when its becoming a dependance issue again.
ya as someone who smokes a lot of weed. its not addictive as in like, i get the shakes if i dont smoke but its def more than peanut butter cups
its def addicting, just not physically so. i feel real uncomfortable if my smoke habit gets disrupted.
That’s pretty much a habit, I also get uncomfortable when I have to go out when I always have that day free. Peanut butter cups might not be a good example because the sugar is really bad for humans.